Analysis of postoperative pain score and risk of lung infection after liver resection based on propensity score matching

Abstract

Abstract: Objective: To investigate the relationship between postoperative pain score and pulmonary infection after liver resection for liver cancer.
Method: A retrospective selection of 270 patients with liver cancer who underwent hepatectomy in Hezhou People's Hospital from March 2015 to October 2020 was used as the research object. Numerical rating scal (NRS) was used to enter the ward within 24 hours after anesthesia consciously. The patients were scored for pain, and patients with NRS≤3 points were included in the low NRS group (n=175), and patients with NRS>3 points were included in the high NRS group (n=95). Use the propensity score matching method to match the NRS low group with the NRS high group at a ratio of 1:1. The matching factors include age, history of cerebrovascular accident, past history of lung disease, preoperative deep vein puncture, preoperative hospital stay, Operation time, intraoperative blood loss, postoperative ventilator use, nasogastric tube indwelling time, abdominal drainage tube indwelling time, and preoperative white blood cell, procalcitonin (PCT), C-reactive protein (CRP) levels. Compare the baseline data of the low NRS group and the high NRS group before and after matching, and the incidence of postoperative lung infection.
Results: Before matching, there were significant differences in some baseline data between the two groups (P<0.05), and there was no significant difference in the incidence of lung infection between the low NRS group and the high NRS group (P>0.05). After matching, the differences in the matching variables between the two groups were not statistically significant (P>0.05). The incidence of postoperative lung infection in the low NRS group (8.1%) was significantly lower than that in the high NRS group (21.0%) (P<0.05) .
Conclusion: There is a certain correlation between postoperative pain score and pulmonary infection after hepatectomy for liver cancer. Severe postoperative pain may increase the risk of pulmonary infection after hepatectomy. Therefore, clinically, patients are actively evaluated for postoperative pain, and analgesic interventions are given as early as possible to eliminate or alleviate patients' pain and reduce the risk of postoperative lung infection.

Key words: Propensity score matching, Postoperative pain score, Liver cancer, Hepatectomy, Lung infection

Huang Yongchu, Cai Ruiqiang, Liu Nian, Zhou Fengsheng, Mao Xianshuang. Analysis of postoperative pain score and risk of lung infection after liver resection based on propensity score matching[J]. Electronic Journal of Liver Tumor, 2022, 9(3): 17-21.

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