Abstract: The local treatments of liver tumors included surgical procedures, interventional procedures, thermal ablation, cryoablation treatment and other treatments, which can cure most liver tumors. But for the hepatic hilar tumors, Due to the special part of the lesion location adjacent to blood vessels, nerve, biliary and other important structure, the tumor resection rate or damage rate, tumor around the protection of pipe structure, treatment injury, cirrhosis patients with residual liver protection, complications reduction must achieve a good balance. However,the traditional local treatmenst have limitations. Due to the advantages of irreversible electroporation (IRE) ablation technology, such as guidance of cell apoptosis, protect blood vessels, bile duct and other important structures, the application of IRE technology for the ablation of tumors in the special parts of the hepatic portal region has more obvious effectiveness and safety advantages. This review mainly introduces the principle, effectiveness and safety of IRE ablation in special parts of hepatic portal region compared with traditional thermal ablation.

Key words: Irreversible electroporation, Hepatic hilar tumors, Efficacy, Safety