Electronic Journal of Liver Tumor ›› 2024, Vol. 11 ›› Issue (4): 36-41.

• Original article • Previous Articles     Next Articles

The application value of contrast-enhanced ultrasound on the differentiation of colorectal cancer liver metastasis and atypical hepatic hemangioma

Chen Yuxiang1, Yan Ji1, Zhang Chenxue1, Yu Haitao1, Wu Xueliang2, Wang Likun3,*   

  1. 1. Department of ultrasound, Zhangjiakou First Hospital, Zhangjiakou 075000, Hebei, China;
    2. Department of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China;
    3. Department of Ultrasound Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China
  • Received:2024-06-26 Online:2024-12-30 Published:2025-02-25
  • Contact: *Wang Likun, E-mail: wanglikun@tmu.edu.cn

Abstract: Objective: To explore the clinical application value of contrast-enhanced ultrasound (CEUS) in differentiating between colorectal cancer liver metastasis (CCLM) and atypical hepatic hemangioma (AHH).
Method: A retrospective analysis was conducted on patients diagnosed with 76 cases of CCLM and 80 cases of AHH between 2020 and 2022, who underwent CEUS and received pathological confirmation at our institution. The ultrasonographic characteristics of both groups were compared. The diagnostic sensitivity, specificity, accuracy, and receiver operating characteristic (ROC) curves were analyzed for conventional ultrasound alone and in combination with CEUS.
Result: The results indicated significant differences in ultrasound enhancement features between CCLM and AHH, with statistically significant differences in tumor lesion internal and surrounding blood flow signals (P<0.05). Conventional ultrasound combination with CEUS significantly improved the specificity and accuracy in diagnosing CCLM compared to conventional ultrasound alone. Furthermore, the area under the curve for conventional ultrasound combination with CEUS was significantly higher than that for conventional ultrasound.
Conclusion: CEUS is an effective method for enhancing the ultrasound differentiation capability between CCLM and AHH.

Key words: Colorectal cancer liver metastasis, Atypical hepatic hemangioma, Contrast-enhanced ultrasound