Electronic Journal of Liver Tumor ›› 2020, Vol. 7 ›› Issue (2): 48-51.

• Review • Previous Articles     Next Articles

Research progress of apatinib in treatment of hepatocellular carcinoma

Zhao Haoran, Zhang Yubao*   

  1. Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081, Heilongjiang, China
  • Received:2020-05-11 Online:2020-06-30 Published:2020-07-23

Abstract: For many years, the incidence and mortality of primary liver cancer in China have been in the top five, with high recurrence rate and poor prognosis. Based on China's national conditions, the pathological type of primary liver cancer is mainly hepatitis-related hepatocellular carcinoma (HCC). Therefore, the research for HCC can provide crucial reference on the treatment and research on primary liver cancer. Apatinib is a small molecule VEGFR tyrosine kinase inhibitor independently developed in our country. Its safety and effectiveness in HCC treatment have been continuously verified in clinical treatments. It has considerable research potential and prospect. This article reviews the current application status and research progress of apatinib in HCC, aiming to provide valuable reference basis for clinical application.

Key words: Apatinib, Hepatocellular carcinoma, Research progress