Advances of biomarker for efficacy prediction in targeted therapy and immunotherapy of hepatocellular carcinoma

Abstract

Abstract: Hepatocellular carcinoma (HCC) is the most common malignant liver tumor in China, which is seriously threating the life and health of our people. At present, molecular targeted therapy and immunotherapy are the mainly systematic treatment for advanced HCC. How to choose multi-targeted inhibitor and appropriate immunotherapy has become a research hotspot nowadays. With the continuous development of various sequencing technology, exploring the biomarkers of molecular targeted therapy and immunotherapy can precise select the beneficial population as well as predict drugs efficacy and disease prognosis. In this paper, we will review the advances of biomarker for efficacy prediction in targeted therapy and immunotherapy of hepatocellular carcinoma.

Key words: Hepatic carcinoma, Molecular targeted therapy, Immunotherapy, Biomarkers

He Jian, Chen Xiaoming. Advances of biomarker for efficacy prediction in targeted therapy and immunotherapy of hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2020, 7(3): 39-42.

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