Local therapy for unresectable intrahepatic cholangiocarcinoma

Abstract

Abstract: Intrahepatic cholangiocarcinoma refers to a malignant tumor that originates from the epithelial cells of the secondary bile duct and the branches of the intrahepatic bile duct. With the characteristics of difficult early diagnosis, high malignancy and poor prognosis. Although intrahepatic cholangiocarcinoma is relatively rare, it’s still the second most common primary malignant tumor of the liver following the hepatocellular carcinoma. In recent years, the morbidity and mortality of intrahepatic cholangiocarcinoma have been increasing. Surgical resection is currently the only radical cure, but most patients have lost the opportunity for surgery when they are diagnosed. With local treatment technology has made great progress. Those patients with unresectable intrahepatic cholangiocarcinoma, could get benefits from local treatment in terms of tumor burden reducing, symptoms relieved, prolong survival, and even transforming to surgery available. The current common local treatment methods mainly include: ablation treatment, transvascular treatment and radiotherapy. This article reviews the current status and progress of the main local treatments for intrahepatic cholangiocarcinoma. In order to get more approaches to multiple discipline therapy in intrahepatic cholangiocarcinoma.

Key words: Intrahepatic Cholangiocarcinoma, Local Therapy, Ablation, Transarterial Therapy, Radiation Therapy

Li Shupei, Yu Chenxi, Lai Fengyong, Song Peng, Du Chunxia, Yao xuesong. Local therapy for unresectable intrahepatic cholangiocarcinoma[J]. Electronic Journal of Liver Tumor, 2020, 7(4): 44-47.

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