Research progress of serum markers for early diagnosis of hepatocellular carcinoma

Abstract

Abstract: Hepatocellular carcinoma is a malignant tumor originating from liver cells, which is characterized by high degree of malignancy, difficulty in early diagnosis, and poor clinical prognosis. In recent years, more and more studies have found that the sensitivity of serum alpha-fetoprotein for the diagnosis of hepatocellular carcinoma is reduced, and the early diagnostic efficacy is poor. Therefore, the study of new serum tumor markers for hepatocellular carcinoma has become a hot spot. For example, the presence of alpha-fetoprotein heteroplasmy, heat shock protein 90, and Golgi protein 73 may effectively improve the early diagnosis rate of hepatocellular carcinoma. This article reviews the research progress of serum markers for early diagnosis of hepatocellular carcinoma in recent years.

Key words: Hepatocellular carcinoma, Alpha-fetoprotein, fetoprotein L3, Heat-shock protein 90, Golgi protein 73

Fu Zuojun, Liu Guisheng. Research progress of serum markers for early diagnosis of hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2021, 8(3): 51-54.

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