Laparoscopic versus open mesohepatectomy for centrally located hepatocellular carcinoma: a propensity score matching study

Abstract

Abstract: Objective: To compare open and laparoscopic mesohepatectomy for centrally located hepatocellular carcinoma by propensity score matching (PSM).
Methods: The clinical data of 130 patients with centrally located hepatocellular carcinoma treated by surgery from January 2011 to December 2017 were collected. There were 60 patients and 70 patients in the laparoscopic group and the open group all treated by anatomical mesohepatectomy (Ⅳ,Ⅴ,Ⅷ segment) and the short-term and long-term outcomes were collected.
Results: There was no significant difference in baseline data between the two groups after matching by propensity score (P>0.05). Laparoscopy was associated with lower blood loss and shorter postoperative hospital stay (P<0.05). The operation time, blood transfusion rate and complications rate were similar in open and laparoscopic groups (P>0.05). The 3 and 5-year overall survival rates and disease-free survival rates were similar in open and laparoscopic groups (P>0.05).
Conclusion: Laparoscopic anatomic hepatectomy for centrally located hepatocellular carcinoma can be carried out safely with favorable short-term and long-term outcomes.

Key words: Laparoscopy, Mesohepatectomy, Centrally located hepatocellular carcinoma, Treatment outcomes

Leng Songyao, Cao Li, Tian Feng, Wang Xiaojun, Chen Jian, Zheng Shuguo, Li Jianwei. Laparoscopic versus open mesohepatectomy for centrally located hepatocellular carcinoma: a propensity score matching study[J]. Electronic Journal of Liver Tumor, 2021, 8(4): 17-20.

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