Electronic Journal of Liver Tumor ›› 2021, Vol. 8 ›› Issue (4): 31-35.

• Review • Previous Articles     Next Articles

Progress of application of real-time virtual navigation system combined with indocyanine green staining in anatomical liver resection of primary hepatic carcinoma

Dou Xiaowei1, Wang Qiang2, Pu Changsheng2, Shi Wenzai2, Suo Xiaopeng2, Wu Xianjia2, Wu Tiantian2, Cai Jun2, Cheng Zhilei2, Tian Yuanhu2, Chen Jianfei2, Zhang Keming2,*   

  1. 1. Department of Hepatobiliary Surgery, Yidu Central Hospital of Weifang, Weifang 262500, Shandong, China;
    2. Department of Hepatobiliary Surgery, Peking University International Hospital, Beijing 102206, China
  • Received:2021-09-03 Online:2021-12-30 Published:2022-10-27

Abstract: The current preferred treatment for primary hepatic carcinoma is hepatectomy. However, the recurrence rate after hepatectomy is high, and the overall treatment effect is not satisfactory. The prognosis of anatomical liver resection is better than that of non-anatomical liver resection, which is gradually accepted by everyone. However, in anatomical liver resection, how to identify the tumor boundary, small intra-hepatic lesions, and the segmentation of the liver segment is still clinically facing problem. In recent years, real-time virtual navigation system (RVS) technology has been gradually applied in clinics. RVS is a complete fusion of ultrasound and CT, MRI and other imaging images. Its resolution and localization detection rate of liver cancer lesions and surrounding normal liver tissues are better than conventional intraoperative ultrasound. Indocyanine green (ICG) fluorescent staining can mark micrometastasis and liver segmentation off-line. Previous studies have shown that the use of RVS real-time dynamic navigation combined with ICG staining during surgery to eventually complete accurate anatomical liver resection can increase R0 resection rate, reduce the postoperative recurrence rate and metastasis rate of primary hepatic carcinoma, and improve primary hepatic carcinoma prognosis.

Key words: Primary hepatic carcinoma, Anatomical liver resection, Indocyanine green staining, Real-time virtual navigation system