A meta-analysis of the safety and effectiveness of laparoscopic liver resection for lesions located in posterosuperior versus anterolateral segments

Abstract

Abstract: Objective: To comprehensively evaluate and compare the safety and effectiveness of laparoscopic liver resection (LLR) for posterosuperior lesions versus anterolateral lesions.
Methods: A comprehensive search of literature during March 2001 and March 2021 on LLR for posterosuperior lesions versus anterolateral lesions was conducted. Literatures that met the criteria were included. Meta-analysis was performed on intraoperative outcome indicators, short-term postoperative outcome indicators and long-term outcome indicators.
Results: Compared with LLR for anterolateral lesions, the operation time was significantly longer, and conversion rate was significantly increased (P<0.0001) in LLR for posterosuperior lesions. There were no significant difference in intraoperative blood loss, intraoperative blood transfusion rate, surgical margin distance, pringle maneuver duration, postoperative hospital stay, postoperative complications (P>0.05). Among them, for patients with malignant tumors, there was no relationship between postoperative tumor-free survival as well as overall survival and tumor location (P>0.05).
Conclusion: Although LLR for lesions located in posterosuperior segments is difficult, it is a safe, effective and feasible minimally invasive surgical method that may be more beneficial to patients after the laparoscopic technique is mature.

Key words: Laparoscope, Hepatectomy, Posterosuperior segment, Anterolateral segment, Meta analysis

Wang Yuxin, Xing Jiali, Liu Xiao, Wan Xueshuai, Zheng Yongchang, Xu Haifeng, Du Shunda, Mao Yilei. A meta-analysis of the safety and effectiveness of laparoscopic liver resection for lesions located in posterosuperior versus anterolateral segments[J]. Electronic Journal of Liver Tumor, 2021, 8(4): 6-12.

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