Electronic Journal of Liver Tumor ›› 2022, Vol. 9 ›› Issue (2): 23-27.

• Review • Previous Articles     Next Articles

Research progress of spontaneous ruptured hepatocellular carcinoma

Huang Xiaozhun1, Wang Chunling1, Liu Yibin2, Li Xiaoqing1, Huang Zhangkan1, Xu Lin1, Ni Yong3, Che Xu1,4, Bi Xinyu5,*   

  1. 1. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong, China;
    2. Department of General Surgery, Longgang District Central Hospital of Shenzhen, Shenzhen 518116, Guangdong, China;
    3. Department of Hepatopancreatobiliary Surgery, Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, Guangdong, China;
    4. Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China;
    5. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2022-02-07 Published:2022-10-26

Abstract: Spontaneously ruptured hepatocellular carcinoma (rHCC) with hemorrhage is characterized by rapid onset and progression, the pathogenesis is not clear, and liver background in rHCC patients was complicated. There is large heterogeneity between different ways of handling the survival benefit obtained, the choice of clinical decision caused great distress, so looking for some indicators or model to predict the treatment of patients with rHCC forecast is of great significance. This article is based on the existing clinical evidence, this article will review the research progress of rHCC with hemorrhage: From the rupture mechanism of hepatocellular carcinoma (HCC) are expounded of high burst tendency HCC of the operation time. Different treatments of short- and long-term survival benefit with multiple model prediction effect for the treatment of rHCC. Finally we explored the treatment of rHCC survivors.

Key words: Hepatocellular carcinoma, Spontaneously ruptured, Hepatectomy, Survival, Prediction model