Electronic Journal of Liver Tumor ›› 2024, Vol. 11 ›› Issue (1): 16-20.

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Research progress on conversion therapy for patients with malignant liver tumors with inadequate remnant liver volume

Li Xin, Li Zhiyu*   

  1. Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China
  • Received:2024-01-26 Online:2024-03-31 Published:2024-05-08
  • Contact: *E-mail:lizhiyu2004@sina.com

Abstract: For patients with primary or locally metastatic malignant liver tumors,the only chance for long-term survival is complete resection of the liver tumors. However, post-hepatectomy liver failure(PHLF) remains a major cause of mortality after liver resection,and inadequate future liver remnant has been proven to be a major risk factor for PHLF. Currently,various methods exist for preoperative conversion therapy. Portal vein embolization and associating liver partition and portal vein ligation for staged hepatectomy are the two most widely used methods. However, each method has its distinct advantages and disadvantages. With the development of comprehensive treatment for malignant tumors, several treatment methods are under exploration. This study compares different conversion therapy methods,aiming to provide clinical references.

Key words: Malignant liver tumors, Future liver remnant, Conversion therapy