Progress on immune mechanism of traditional Chinese medicine regulating gut microbiota and its metabolites in the occurrence and development of liver cancer

Abstract

Abstract: Traditional Chinese Medicine plays an indispensable role in the clinical treatment of tumor, especially in comprehensive adjuvant therapy, it can significantly reduce the adverse reactions caused by radiotherapy, chemotherapy, targeted therapy and immunotherapy, collection of treatment and health in one and strengthening healthy to eliminate pathogens. At the same time, the intestinal microflora and its metabolites are regulated to increase beneficial bacteria and reduce harmful bacteria, repair the intestinal microenvironment, regulate bile acid (BA) metabolism and immune factor expression, exert immune response, and then improve the liver regeneration microenvironment to inhibit the occurrence and development of liver cancer. This review will start with the regulation of intestinal flora by traditional Chinese medicine and explain its immune mechanism in liver cancer.

Key words: Liver cancer, Traditional Chinese Medicine, Gut microbiota, Bile acid, Immune mechanism

Li Cunya, Fu Shujuan, Li Yun, Zhong Zhixian, Wang Zhiying, Zhong Yi. Progress on immune mechanism of traditional Chinese medicine regulating gut microbiota and its metabolites in the occurrence and development of liver cancer[J]. Electronic Journal of Liver Tumor, 2022, 9(1): 61-64.

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