The significance of cystatin SN expression in hepatocellular carcinoma

Abstract

Abstract: Objective: To analyze the expression level of cystatin Sn in HCC and its relationship with clinicopathological features, and to explore the relationship between the expression level of cystatin SN and the prognosis of HCC patients. Methods: The clinical data of 72 patients with primary liver cancer were collected, and the expression of cystatin SN was detected by immunohistochemistry in 72 HCC and 60 paraffin samples of paracancerous tissues. Results: The expression intensity of cystatin SN was significantly higher than that of HCC (P<0.05). The patients with high expression level of cystatin SN in HCC were better than those with low expression level in disease-free survival and overall survival (P<0.05). Conclusion: The expression of cystatin SN in HCC is significantly lower than that in paracancerous tissues, and the HCC patients with high expression of cystatin SN were significantly better than those with low expression in disease-free survival and overall survival.

Key words: Hepatocellular carcinoma, Cystatin SN, Disease-free survival, Overall survival

Wu Jie, Gao Fei, Zhang Xuesong, Wang Kuiyang, Sui Chengxu, Zhang Liang, Yao Yuanfang, Song Lei. The significance of cystatin SN expression in hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2021, 8(2): 33-38.

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