Electronic Journal of Liver Tumor ›› 2021, Vol. 8 ›› Issue (2): 39-42.

• Review • Previous Articles     Next Articles

Research progress on the influence of margin width on the prognosis of hepatocellular carcinoma

Huang Xiaozhun1, Wang Chunling2, Huang Zhangkan1, Xu Lin1, Zhang Renjie1, Bi Xinyu3, Che Xu1,4,*, Zhao Jianjun3,*   

  1. 1. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong, China;
    2. Department of Hepatology, Huizhou Municipal Central Hospital, Huizhou 516001, Guangdong, China;
    3. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China;
    4. Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2020-01-15 Published:2021-07-16

Abstract: Hepatectomy is still the main treatment for liver malignant tumors. Surgical resection can improve the survival and prognosis of hepatocellular carcinoma. However, the influence of the width of the surgical margin on the survival prognosis of hepatocellular carcinoma is still controversial. Based on the existing literature evidence, this article will review the relationship between the width of surgical margins and the survival and prognosis of hepatocellular carcinoma, therefore, trying to explain the clinical research progress of surgical margins from microvascular invasion and circulating tumor cells.

Key words: Hepatocellular carcinoma, Liver resection, Surgical margin, Microvascular invasion, Circulating tumor cell