结直肠癌肝转移手术和新辅助化疗策略

摘要/Abstract

摘要： 结直肠癌的发病率及死亡率在国内逐年上升,肝转移是患者死亡的主要原因之一。随着个体化治疗及多学科综合治疗协作组(multiple disciplinary team, MDT)诊治理念的提出,以及外科技术、新辅助化疗的迅速发展,患者的生存时间得到明显延长。目前,根治性手术治疗仍是治愈结直肠癌肝转移的主要方法,局部毁损治疗作为手术治疗的有效补充也已广泛应用于临床。新辅助化疗的应用可以降低肿瘤分期,提高手术切除率。但对于结直肠癌肝转移患者的手术方式、手术时机及新辅助化疗中是否联合靶向药物等仍存在争议。本文就结直肠癌肝转移手术和新辅助化疗进展展开综述。

关键词: 结直肠肿瘤, 肿瘤转移, 结直肠癌肝转移, 新辅助化疗, 局部治疗

包满都拉, 苏昊, 罗寿, 徐正, 明光, 梁建伟, 刘正, 刘骞, 周志祥, 王锡山, 周海涛. 结直肠癌肝转移手术和新辅助化疗策略[J]. 肝癌电子杂志, 2020, 7(1): 45-50.

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