法尼酯X受体在肝癌中的研究进展

摘要/Abstract

摘要： 法尼酯X受体（FXR）是配体激活的一种转录因子,参与控制胆汁酸的合成和肠肝循环。近年来越来越多的研究表明FXR在肝癌中的表达与肝细胞癌的多种恶性临床病理特征呈负相关。本文就FXR在肝癌中的研究进展作一综述,以期为肝癌的防治提供必要的借鉴和参考。

关键词: 法尼酯X受体, 胆汁酸, 肝癌

Abstract: Farnesoid X receptor (FXR) is a ligand-activated transcription factor involved in the control of bile acid synthesis and enterohepatic circulation. In recent years, more and more studies have shown that the expression of hepatic FXR is inversely correlated with multiple malignant clinicopathological characteristics of hepatocellular carcinoma. This article reviewed the advances in study on FXR in hepatocellular carcinoma to provide necessary reference for the prevention and treatment of hepatocellular carcinoma.

Key words: Farnesoid X receptor, Bile acid, Liver cancer

赵卫华, 李长英. 法尼酯X受体在肝癌中的研究进展[J]. 肝癌电子杂志, 2025, 12(2): 22-25.

Zhao Weihua, Li Changying. Advances in study on farnesoid X receptor in hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2025, 12(2): 22-25.

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