肝移植受者肌少症发生现状及其影响因素分析

肝癌电子杂志 ›› 2026, Vol. 13 ›› Issue (1): 22-27.

肝移植受者肌少症发生现状及其影响因素分析

刘薪¹, 郭凤娟², 张莉莉³, 谷艳梅¹, 席双梅¹, 刘新星², 郑煜琳¹, 王宏^2,*

1.首都医科大学附属北京佑安医院重症医学科,北京 100069;
2.首都医科大学附属北京佑安医院器官移植中心,北京 100069;
3.首都医科大学附属北京佑安医院护理部,北京 100069

收稿日期:2025-11-21 出版日期:2026-03-30 发布日期:2026-05-21
通讯作者: ^* 王宏,E-mail: wanghongwg@sina.com

Analysis of the prevalence and influencing factors of sarcopenia in liver transplant recipients

Liu Xin¹, Guo Fengjuan², Zhang Lili³, Gu Yanmei¹, Xi Shuangmei¹, Liu Xinxing², Zheng Yulin¹, Wang Hong^2,*

1. Department of Intensive Care Unite, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China;
2. Organ Transplantation Center, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China;
3. Department of Nursing, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China

Received:2025-11-21 Online:2026-03-30 Published:2026-05-21
Contact: ^* Wang Hong, E-mail: wanghongwg@sina.com

摘要/Abstract

摘要： 目的：调查肝移植受者肌少症发生率及其影响因素,为制订肝移植术后康复管理策略提供依据。
方法：采用横断面研究设计,便利抽样选取2025年4—10月在首都医科大学附属北京佑安医院肝移植门诊就诊的患者为研究对象。通过患者的肌肉质量、肌肉力量及躯体功能判断肌少症。采用一般资料调查表、国际体力活动问卷短版、营养风险筛查2002、领悟社会支持量表收集患者资料。采用单因素分析及多因素Logistic 回归分析探讨肝移植受者肌少症的影响因素。
结果：本研究共纳入128例患者,肌少症发生率为17.2%。单因素分析结果显示两组在年龄、性别、体重指数、白蛋白、社会支持水平方面差异均有统计学意义（均P<0.05）,多因素Logistic分析显示性别、年龄、体重指数、白蛋白、社会支持水平是肝移植受者肌少症的影响因素。
结论：肝移植术后肌少症发生率较高,其发生受生物学特征、营养状况及社会支持等因素共同影响。应在术后随访中加强监测,关注女性、高龄及白蛋白水平低等高风险人群;并从营养支持、体力活动管理及社会心理支持等方面实施综合干预,以减少肌少症发生,促进术后康复。

关键词: 肝移植, 肌少症, 因素分析

Abstract: Objective: To investigate the prevalence of sarcopenia among liver transplant (LT) recipients and identify its associated factors, thereby providing evidence for developing postoperative rehabilitation strategies.
Methods: A cross-sectional study was conducted using convenience sampling among LT recipients attending the outpatient clinic of Beijing You'an Hospital from April to October 2025. Sarcopenia was diagnosed based on muscle mass, muscle strength, and physical performance. Data were collected using a general information questionnaire, the short form international physical activity questionnaire, the nutrition risk screening 2002, and the perceived social support scale. Univariate analysis and logistic regression were employed to determine the influencing factors of sarcopenia.
Results: A total of 128 participants were included, and the prevalence of sarcopenia was 17.2%. The univariate analysis revealed no significant differences between the two groups in terms of age, gender, BMI, albumin, or levels of social support (all P<0.05). Multivariate analysis indicated that sex, age, body mass index, serum albumin level, and perceived social support were independently associated with sarcopenia in LT recipients.
Conclusions: Sarcopenia is relatively common after liver transplantation and is influenced by multiple dimensions, including biological characteristics, nutritional status, and social support. Enhanced monitoring should be implemented during postoperative follow-up, with special attention paid to high-risk groups including female patients, elderly individuals, and those with low albumin levels. Comprehensive interventions should be carried out from aspects such as nutritional support, physical activity management, and psychosocial support to reduce the incidence of sarcopenia and promote postoperative rehabilitation.

Key words: Liver transplantation, Sarcopenia, Factors analysis

刘薪, 郭凤娟, 张莉莉, 谷艳梅, 席双梅, 刘新星, 郑煜琳, 王宏. 肝移植受者肌少症发生现状及其影响因素分析[J]. 肝癌电子杂志, 2026, 13(1): 22-27.

Liu Xin, Guo Fengjuan, Zhang Lili, Gu Yanmei, Xi Shuangmei, Liu Xinxing, Zheng Yulin, Wang Hong. Analysis of the prevalence and influencing factors of sarcopenia in liver transplant recipients[J]. Electronic Journal of Liver Tumor, 2026, 13(1): 22-27.

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