肝癌电子杂志 ›› 2026, Vol. 13 ›› Issue (3): 29-33.

• 专题 • 上一篇    下一篇

结直肠癌肝转移外科手术治疗

刘伟, 邢宝才   

  1. 北京大学肿瘤医院暨北京市肿瘤防治研究所外科 恶性肿瘤发病机制及转化研究教育部重点实验室,北京 100142
  • 收稿日期:2026-07-13 出版日期:2026-09-30 发布日期:2026-10-28

The surgical treatment of colorectal liver metastases

Liu Wei, Xing Baocai   

  1. Department of Radiation Oncology, Peking University Cancer Hospital and Beijing Cancer Prevention and Treatment Institute; Key Laboratory of Tumor Pathogenesis and Metastasis, Ministry of Education, Beijing 100142, China
  • Received:2026-07-13 Online:2026-09-30 Published:2026-10-28

摘要: 根据我国国家癌症中心全国癌症报告,截至2022年,结直肠癌由2013年的第4位已上升至第 2 位,结直肠癌死亡病例由 2013 年的第 5 位上升至第 4位,成为目前严重威胁人民生命健康的疾病。与结直肠癌的不良预后及死亡密切相关的因素是结直肠癌肝转移。近30年的数据积累显示:结直肠癌肝转移的患者,采用系统治疗联合手术治疗,其5年生存率可为40%-50%,部分患者可以获得治愈。结直肠癌肝转移之所以可以获得如此好的长期生存,切除肝转移灶发挥了重要的作用。随着结直肠癌发病率的增加,肝转移患者数量也在逐年增多。笔者认为:需要肝脏外科医师积极参与肝转移的多学科诊断与治疗,根据不同情况,为肝转移患者提供规范化的个体化局部治疗。如何在诸多外科的局部治疗手段中,选择适合的治疗方式,针对患者制定合理的治疗方案,这需要肝脏外科医师不断提高自己的知识水平,更新治疗理念。

关键词: 结直肠肿瘤, 肝转移, 外科治疗, 诊断, 治疗

Abstract: According to the National Cancer Report by the National Cancer Center of China, as of 2022, the incidence ranking of colorectal cancer has risen from 4th to 2nd, and its mortality ranking has increased from 5th to 4th, making it a disease that currently poses a severe threat to public health and survival. The factor most closely associated with the poor prognosis and mortality of colorectal cancer is colorectal liver metastasis (CRLM). Data accumulated over the past three decades have demonstrated that patients with CRLM treated with systemic therapy combined with surgical resection can achieve a 5 year survival rate of 40%-50%, and some patients can be cured. Resection of liver metastases plays a crucial role in achieving such favorable long term survival. With the rising incidence of colorectal cancer, the number of patients with liver metastasis continues to increase annually. The authors believe that hepatic surgeons should actively participate in the multidisciplinary diagnosis and treatment of liver metastases, and provide standardized and individualized local treatment for patients with CRLM based on specific clinical conditions.
To select appropriate local surgical therapies and develop rational treatment strategies for individual patients, hepatic surgeons must continuously improve their professional knowledge and update treatment concepts.

Key words: Colorectal cancer, Liver metastasis, Surgical treatment, Diagnosis, Treatment