Abstract: Hepatic surgery, characterized by complex anatomy and high surgical risks, confronts predicaments in clinical practice including uneven distribution of medical resources, insufficient surgical precision, and low efficiency in remote collaboration in clinical practice. In the field of education, it encounters problems such as abstract and hard-to-understand knowledge, scarce practical opportunities, and unbalanced resource distribution. The deep integration of artificial intelligence (AI) and fifth-generation communication technology (5G) offers a potential solution to these problems. The application of AI and 5G in the medical and educational collaboration of liver surgery is expected to achieve the future development goals of high precision, wide coverage, and strong inheritance in liver surgery through new ideas, methods, and technologies of medical and educational collaboration. Moreover, by leveraging innovative technological transformation means, it can broaden the dimension of technological innovation and enhance the breadth of technological application, playing a greater role in the future medical and educational collaboration of liver surgery.

Key words: Artificial intelligence, Fifth generation mobile communication technology, Hepatic surgery, Medical-educational synergy