肝癌电子杂志 ›› 2020, Vol. 7 ›› Issue (2): 52-55.

• 综述 • 上一篇    下一篇

大数据助力肝胆恶性肿瘤诊疗探索

卢姗姗, 贾晓东, 张宁, 曾珍, 陆荫英*   

  1. 中国人民解放军总医院第五医学中心肝脏肿瘤诊疗与研究中心,北京 100039
  • 收稿日期:2020-01-15 出版日期:2020-06-30 发布日期:2020-07-23
  • 通讯作者: * 陆荫英 E-mail: luyinying1973@163.com
  • 作者简介:陆荫英,教授,中国人民解放军总医院第五医学中心 肝脏肿瘤诊疗与研究中心。
  • 基金资助:
    国家科技重点专项(2017YFC0908401); 国家科技重大专项(2018ZX10723204-007-002); 北京市科技计划(Z181100001718075 )

Exploration on diagnosis and treatment of hepatobiliary malignancies by big data

Lu Shanshan, Jia Xiaodong, Zhang Ning, Zeng Zhen, Lu Yinying*   

  1. Comprehensive Liver Cancer Center, the Fifth Medical Center of PLA General Hospital, Beijing 100039, China
  • Received:2020-01-15 Online:2020-06-30 Published:2020-07-23

摘要: 肝胆恶性肿瘤是消化系统中比较常见的一类疾病,其发病隐匿,进展速度快,尤其是进展到晚期的肝胆恶性肿瘤,其低根治率和高死亡率仍是临床上比较棘手的主要问题之一。近年来,随着大数据时代的悄然崛起,精准诊疗计划的不断推进,一些新的临床决策、诊疗策略也大量涌现。在肝胆恶性肿瘤领域,大数据与精准医疗的完美结合,将有利于众多医学者更加深入、全面地了解肝胆恶性肿瘤的生物学特点,进而揭示肝胆恶性肿瘤的驱动基因和发病机制;大数据的整合分析,也会推动个体化、精确化医疗的实施,进而提高临床肝胆恶性肿瘤的规范化诊疗水平,为突破晚期肝胆恶性肿瘤治疗瓶颈带来新的曙光和希望。

关键词: 大数据, 精准医学, 肝胆恶性肿瘤, 个体化治疗

Abstract: Hepatobiliary malignancies are common in digestive system diseases, which are occult and develop rapidly, especially in advanced hepatobiliary malignancies, it's low radical cure rate and high mortality are still one of the most difficult problems in clinical practice. In recent years, with the rise of big data and the advancement of accurate diagnosis and treatment plan, a number of new clinical decisions and treatment strategies have emerged. In the field of hepatobiliary malignancies, the perfect combination of big data and precision medicine will help many medical scholars to understand the biological characteristics of hepatobiliary malignancies more deeply and comprehensively, and then reveal the driving genes and pathogenesis of hepatobiliary malignancies; The integration and analysis of big data will also promote the implementation of individualized and precision medicine, and improve the standardized diagnosis and treatment level of hepatobiliary malignancies. In addition, it can also bring new light and hope for breaking through the bottleneck of treatment of advanced hepatobiliary malignancies.

Key words: Big data, Precision medicine, Hepatobiliary malignancies, Individualized medicine