肝细胞癌免疫治疗的现状及研究进展

肝癌电子杂志 ›› 2020, Vol. 7 ›› Issue (2): 56-60.

肝细胞癌免疫治疗的现状及研究进展

邵巍伟^1,2, 孙振^1,3, 宋京海^1,*

1 北京医院普通外科/国家老年医学中心/中国医学科学院老年医学研究院,北京 100730;
2 中国医学科学院北京协和医学院北京 100730;
3 北京大学医学部,北京 100730

收稿日期:2020-04-11 出版日期:2020-06-30 发布日期:2020-07-23
通讯作者: ^* 宋京海,E-mail：jhaisong2003@163.com
作者简介:宋京海,教授,北京医院普通外科国家老年医学中心中国医学科学院老年医学研究院。
基金资助:
国家自然科学基金(81671581)

Current status and progress of immunotherapy for hepatocellular carcinoma

Shao Weiwei^1,2, Sun Zhen^1,3, Song Jinghai^1,*

1 Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China;
2 Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China;
3 Peking University Health Science Center, Beijing 100730, China

Received:2020-04-11 Online:2020-06-30 Published:2020-07-23

摘要/Abstract

摘要： 原发性肝癌（primary liver cancer,PLC）是最常见的恶性肿瘤之一,其大多数为肝细胞癌（hepatocellular carcinoma,HCC）。肝癌传统治疗方法有手术切除、肝移植、经导管动脉化疗栓塞、消融等,靶向治疗也逐步应用于临床,改善了晚期HCC患者的生存率。但目前对于晚期HCC仍缺乏有效治疗手段。近年来,肝癌的免疫治疗快速发展,受到了越来越多的关注,相关研究也是当前肝癌临床研究的热点之一。本文就当前HCC的免疫治疗研究现状及进展进行综述。

关键词: 肝细胞癌, 免疫治疗, 联合治疗

Abstract: Primary liver cancer (PLC) is one of the most common malignant tumors, and hepatocellular carcinoma (HCC) accounts for the majority. Traditional treatments for HCC include surgical resection, liver transplantation, transcatheter arterial chemoembolization, ablation and so on. Gradually, targeted therapy is applied to clinical treatment for HCC, which improves the patients’ survival rate. However, Effective means is still lacking for advanced HCC. In recent years, immunotherapy for HCC develops rapidly and gets more and more attention, and the relevant studies are hotspots among HCC researches. This article reviews the current status and progress of immunotherapy for HCC.

Key words: Hepatocellular carcinoma, Immunotherapy, Combined treatment

邵巍伟, 孙振, 宋京海. 肝细胞癌免疫治疗的现状及研究进展[J]. 肝癌电子杂志, 2020, 7(2): 56-60.

Shao Weiwei, Sun Zhen, Song Jinghai. Current status and progress of immunotherapy for hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2020, 7(2): 56-60.

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