切缘宽度影响肝细胞癌预后的临床研究进展

肝癌电子杂志 ›› 2021, Vol. 8 ›› Issue (2): 39-42.

切缘宽度影响肝细胞癌预后的临床研究进展

黄小准¹, 王春玲², 黄璋侃¹, 徐林¹, 张仁杰¹, 毕新宇³, 车旭^1,4,*, 赵建军^3,*

1.国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院深圳医院肝胆外科,广东深圳518116;
2.惠州市中心人民医院肝病内科,广东惠州516000;
3.国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院肝胆外科,北京 100021;
4.国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院胰胃外科,北京 100021

收稿日期:2020-01-15 发布日期:2021-07-16
通讯作者: *赵建军,E-mail：13910582458@163.com;车旭,E-mail：drchexu@126.com
作者简介:黄小准,主治医师,中国医学科学院北京协和医学院,肿瘤医院深圳医院,肝胆外科
基金资助:
深圳市“医疗卫生三名工程”项目资助（SZSM202011010）

Research progress on the influence of margin width on the prognosis of hepatocellular carcinoma

Huang Xiaozhun¹, Wang Chunling², Huang Zhangkan¹, Xu Lin¹, Zhang Renjie¹, Bi Xinyu³, Che Xu^1,4,*, Zhao Jianjun^3,*

1. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong, China;
2. Department of Hepatology, Huizhou Municipal Central Hospital, Huizhou 516001, Guangdong, China;
3. Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China;
4. Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Received:2020-01-15 Published:2021-07-16

摘要/Abstract

摘要： 肝切除术仍是肝脏恶性肿瘤的主要治疗手段,手术切除可以提高肝细胞癌的生存预后,但是手术切缘的宽度对肝癌生存预后的影响尚存在争论。本文将基于现有的文献证据对手术切缘的宽度与肝癌的生存预后关系展开综述,并从微血管侵犯及循环肿瘤细胞等多角度阐述肝癌手术切缘的临床研究进展。

关键词: 肝细胞癌, 肝切除, 手术切缘, 微血管侵犯, 循环肿瘤细胞

Abstract: Hepatectomy is still the main treatment for liver malignant tumors. Surgical resection can improve the survival and prognosis of hepatocellular carcinoma. However, the influence of the width of the surgical margin on the survival prognosis of hepatocellular carcinoma is still controversial. Based on the existing literature evidence, this article will review the relationship between the width of surgical margins and the survival and prognosis of hepatocellular carcinoma, therefore, trying to explain the clinical research progress of surgical margins from microvascular invasion and circulating tumor cells.

Key words: Hepatocellular carcinoma, Liver resection, Surgical margin, Microvascular invasion, Circulating tumor cell

黄小准, 王春玲, 黄璋侃, 徐林, 张仁杰, 毕新宇, 车旭, 赵建军. 切缘宽度影响肝细胞癌预后的临床研究进展[J]. 肝癌电子杂志, 2021, 8(2): 39-42.

Huang Xiaozhun, Wang Chunling, Huang Zhangkan, Xu Lin, Zhang Renjie, Bi Xinyu, Che Xu, Zhao Jianjun. Research progress on the influence of margin width on the prognosis of hepatocellular carcinoma[J]. Electronic Journal of Liver Tumor, 2021, 8(2): 39-42.

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