结直肠癌肝脏寡转移立体定向放射治疗的研究进展

摘要/Abstract

摘要： 肝脏是结直肠癌转移最常见的部位。寡转移的患者在系统治疗的基础上接受局部治疗有获得长期生存的可能。立体定向放射治疗（stereotactic radiotherapy,SRT）单次剂量高、分割次数少。本文将综述SRT治疗结直肠癌肝脏寡转移的安全性和有效性,并与其他局部治疗手段进行比较,提供筛选患者的参考标准,以及靶区勾画和剂量限制标准,并探讨新的放射治疗技术、与免疫治疗联合应用为SRT带来的发展。

关键词: 立体定向放射治疗, 结直肠癌, 肝脏寡转移

Abstract: Liver is the most common site of colorectal cancer metastasis. Patients with oligometastasis may achieve long-term survival after local ablative therapy within the context of improved systemic therapy. Stereotactic radiotherapy (SRT) can deliver radical ablative doses in a small number of fractions precisely. We will discuss the safety and efficacy of SRT for liver oligometastatic disease, compare with other local treatment modality, and how to choose patients who can real benefit from SRT. We represent target volume delineation and dose limitation standard. Finally, we discuss the development of new radiotherapy technology and possibility of SRT to combined with systemic therapy.

Key words: Stereotactic radiotherapy, Colorectal cancer, Liver oligometastatic disease

雷俊琴, 金晶. 结直肠癌肝脏寡转移立体定向放射治疗的研究进展[J]. 肝癌电子杂志, 2022, 9(4): 26-31.

Lei Junqin, Jin Jing. Stereotactic radiotherapy for liver oligometastatic disease from colorectal cancer[J]. Electronic Journal of Liver Tumor, 2022, 9(4): 26-31.

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