超声造影在小直径结直肠癌肝转移与非典型血管瘤鉴别诊断中的应用价值

肝癌电子杂志 ›› 2024, Vol. 11 ›› Issue (4): 36-41.

超声造影在小直径结直肠癌肝转移与非典型血管瘤鉴别诊断中的应用价值

陈宇翔¹, 闫骥¹, 张晨雪¹, 於海涛¹, 武雪亮², 王立坤^3,*

1.张家口市第一医院超声科,河北张家口 075000;
2.河北北方学院附属第一医院普外科,河北张家口 075000;
3.河北北方学院附属第一医院超声医学科,河北张家口 075000

收稿日期:2024-06-26 出版日期:2024-12-30 发布日期:2025-02-25
通讯作者: ^*王立坤,E-mail：wanglikun@tmu.edu.cn
基金资助:
2025年度河北省医学科学研究课题计划（20250886）

The application value of contrast-enhanced ultrasound on the differentiation of colorectal cancer liver metastasis and atypical hepatic hemangioma

Chen Yuxiang¹, Yan Ji¹, Zhang Chenxue¹, Yu Haitao¹, Wu Xueliang², Wang Likun^3,*

1. Department of ultrasound, Zhangjiakou First Hospital, Zhangjiakou 075000, Hebei, China;
2. Department of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China;
3. Department of Ultrasound Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China

Received:2024-06-26 Online:2024-12-30 Published:2025-02-25
Contact: ^*Wang Likun, E-mail: wanglikun@tmu.edu.cn

摘要/Abstract

摘要： 目的: 探讨超声造影（contrast-enhanced ultrasonography, CEUS）鉴别诊断直径<30 mm结直肠癌肝转移（colorectal cancer liver metastasis, CCLM）与非典型肝血管瘤（atypical hepatic hemangioma, AHH）的临床应用价值。
方法: 回顾性分析2020—2022年在张家口市第一医院接受CEUS检查并经病理确诊的71例CCLM和85例AHH患者,比较两组患者CEUS特征。比较常规超声对比常规超声联合CEUS的诊断敏感度、特异度、准确性和受试者操作特征曲线。
结果: CCLM与AHH的CEUS特征存在较大差异,两组患者肿瘤病灶内部及周围血流信号差异均有统计学意义（P均<0.05）。常规超声联合CEUS诊断小直径CCLM的特异度和准确性较单纯常规超声检查显著提高。常规超声联合CEUS诊断CCLM的曲线下面积显著高于单纯常规超声。
结论: CEUS能有效提升超声检查鉴别诊断CCLM与AHH的效能。

关键词: 结直肠癌肝转移, 非典型肝血管瘤, 超声造影

Abstract: Objective: To explore the clinical application value of contrast-enhanced ultrasound (CEUS) in differentiating between colorectal cancer liver metastasis (CCLM) and atypical hepatic hemangioma (AHH).
Method: A retrospective analysis was conducted on patients diagnosed with 76 cases of CCLM and 80 cases of AHH between 2020 and 2022, who underwent CEUS and received pathological confirmation at our institution. The ultrasonographic characteristics of both groups were compared. The diagnostic sensitivity, specificity, accuracy, and receiver operating characteristic (ROC) curves were analyzed for conventional ultrasound alone and in combination with CEUS.
Result: The results indicated significant differences in ultrasound enhancement features between CCLM and AHH, with statistically significant differences in tumor lesion internal and surrounding blood flow signals (P<0.05). Conventional ultrasound combination with CEUS significantly improved the specificity and accuracy in diagnosing CCLM compared to conventional ultrasound alone. Furthermore, the area under the curve for conventional ultrasound combination with CEUS was significantly higher than that for conventional ultrasound.
Conclusion: CEUS is an effective method for enhancing the ultrasound differentiation capability between CCLM and AHH.

Key words: Colorectal cancer liver metastasis, Atypical hepatic hemangioma, Contrast-enhanced ultrasound

陈宇翔, 闫骥, 张晨雪, 於海涛, 武雪亮, 王立坤. 超声造影在小直径结直肠癌肝转移与非典型血管瘤鉴别诊断中的应用价值[J]. 肝癌电子杂志, 2024, 11(4): 36-41.

Chen Yuxiang, Yan Ji, Zhang Chenxue, Yu Haitao, Wu Xueliang, Wang Likun. The application value of contrast-enhanced ultrasound on the differentiation of colorectal cancer liver metastasis and atypical hepatic hemangioma[J]. Electronic Journal of Liver Tumor, 2024, 11(4): 36-41.

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