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    Research progress on occupational stress formation of oncology nurses
    A-yun ZHAO, Jing-hui Li, Na Zhuang, Yun Liu
    Electronic Journal of Liver Tumor    2019, 6 (4): 36-38.  
    Abstract168)   HTML6)    PDF (1187KB)(499)       Save

    At present, the incidence of cancer is increasing year by year, and oncology nurses also need to face more and more work pressure. Compared with nurses in general departments, oncology nurses should not only carry out necessary nursing for cancer patients, but also comprehensively master the medication, observation, nursing and psychological counseling for cancer patients. High-intensity work and persistent physical and mental burden not only affect the mental health status of nurses, but also reduce the quality of care. Therefore, from the perspective of occupational stress of nurses in hospital oncology department, this paper makes an in-depth analysis of the factors that affect the pressure of nurses in the daily nursing process, and puts forward corresponding improvement strategies, attaching importance to the professional management of nurses, effectively relieving the pressure of nurses, and promoting the sustainable and healthy development of their mental health and nursing quality.

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    Electronic Journal of Liver Tumor    2019, 6 (4): 9-13.  
    Abstract278)   HTML6)    PDF (1200KB)(457)       Save
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    Electronic Journal of Liver Tumor    2020, 7 (2): 73-75.  
    Abstract70)      PDF (5719KB)(440)       Save
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    Electronic Journal of Liver Tumor    2020, 7 (2): 2-11.  
    Abstract233)      PDF (1680KB)(416)       Save
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    Electronic Journal of Liver Tumor    2024, 11 (3): 1-13.  
    Abstract68)      PDF (1944KB)(398)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (4): 27-31.  
    Abstract155)   HTML6)    PDF (1199KB)(344)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (4): 5-8.  
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    Electronic Journal of Liver Tumor    2020, 7 (2): 66-69.  
    Abstract115)      PDF (5682KB)(328)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (4): 39-42.  
    Abstract160)   HTML6)    PDF (2274KB)(302)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (4): 1-4.  
    Abstract150)   HTML5)    PDF (1201KB)(285)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (3): 22-23.  
    Abstract202)   HTML5)    PDF (864KB)(277)       Save
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    Electronic Journal of Liver Tumor    2023, 10 (4): 1-14.  
    Abstract312)      PDF (2280KB)(277)       Save
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    Electronic Journal of Liver Tumor    2023, 10 (3): 1-11.  
    Abstract153)      PDF (1692KB)(265)       Save
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    Immune Checkpoint Inhibitors in Hepatocellular Carcinoma: Research Progress and Future Perspectives
    Meng HE, Ning Lyu, Ming ZHAO
    Electronic Journal of Liver Tumor    2019, 6 (4): 14-19.  
    Abstract250)   HTML10)    PDF (1290KB)(264)       Save

    Inhibitory checkpoints, including cytotoxic T lymphocyte?Cassociated antigen 4 (CTLA-4), programmed cell death protein-1(PD-1), and programmed cell death ligand 1 (PD-L1), have been identified to suppress anti-tumor immune responses in solid tumors. The application of immune checkpoint inhibitors (ICIs) have reversed immune exhaustion with promising efficacy in practice, which expanded the spectrum of clinical use. Recent output studies show immune checkpoint therapy provides survival benefit for tremendous numbers of patients with hepatocellular carcinoma(HCC). While with remarkable and durable responses in a subset HCC patients, majority of those will still develop primary non-response or adaptive resistance. The combination treatment strategies with immunotherapy is being evaluated in phase 1, 2 or 3 trials in HCC, and some of the results suggested that an anti-PD-1 antibody combined with other ICIs, Tyrosine Kinase Inhibits(TKI), systemic therapy or locoregional therapy are more effective treatment strategies. In this review, we summarise recent developments in ICIs-based therapies, and speculate rational deployment of the effective predictive markers and selection of the combination therapy strategies,which should hold promise for improve the efficacy and prognosis of HCC patients.

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    The prognostic value of simple inflammation-related indexes in predicting liver transplantation for hepatocellular carcinoma
    Cao Yin, Wang Zhongxia, Jiang Chunping
    Electronic Journal of Liver Tumor    2021, 8 (3): 35-40.  
    Abstract60)      PDF (1547KB)(260)       Save
    Liver transplantation is an important treatment for hepatocellular carcinoma, but the recurrence rate remains unsatisfied. Systemic inflammatory response can be reflected by a number of common serological markers including neutrophils, lymphocytes, platelets, C-reactive protein and simple inflammatory indexes constructed by these factors. Many researches reported that these inflammatory indexes are important to predict the prognosis of HCC patients underwent liver transplantation. The purpose of this review is to summarize the published work on the prognostic value of simple inflammation based markers such as neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, lymphocyte-monocyte ratio, systemic immune inflammation index, prognostic nutrient index, and Glasgow prognostic score in HCC patients following liver transplantation.
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    Global liver cancer and gallbladder cancer incidence and mortality in 2020
    Shan Tianhao1, An Lan1, Xu Mengyuan1, Zeng Hongmei1,*, Cai Jianqiang2,*
    Electronic Journal of Liver Tumor    2022, 9 (4): 46-51.  
    Abstract358)      PDF (2337KB)(259)       Save
    Objective:According to the data of GLOBOCAN 2020, we compared the global and Chinese incidence and mortality of liver cancer and gallbladder cancer in 2020, to provide a scientific basis for cancer prevention and control.
    Method:According to the incidence and mortality data of liver cancer and gallbladder cancer released by the International Agency for Research on Cancer in 2020, the differences among different regions, genders and ages were compared.
    Result:In 2020, there were 905 677 new cases and 830 180 deaths of liver cancer globally, with age-standardized incidence and mortality rates of 9.5/100 000 and 8.7/100 000, respectively. For gallbladder cancer, the numbers of new cases and deaths were 115 949 and 84 695, respectively, with the age-standardized incidence and mortality of 1.2/100 000 and 0.84/100 000, respectively. The top five countries with highest incidence of liver cancer were Mongolia, Egypt, Laos, Cambodia and Vietnam. The top five countries with highest incidence of gallbladder cancer were Bolivia, Chile, Bangladesh, Nepal and Korea. In 2020, there were 410 038 new cases of liver cancer in China, with a standardized incidence rate of 18.2/100 000, ranking 8th among all countries. There were 391 152 new cases of death from liver cancer in China, with an age-standardized mortality rate of 17.2/100 000. For gallbladder cancer, there were 28 923 new cases of incidence in China, with an age-standardized incidence rate of 1.2/100 000, ranking 39th among all countries. There were 23 297 new cases of death from gallbladder cancer in China, with an age-standardized mortality rate of 0.97/100 000.
    Conclusion:The disease burden of liver cancer and gallbladder cancer is different between countries. Different prevention and control strategies should be formulated according to different populations.
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    Electronic Journal of Liver Tumor    2019, 6 (3): 14-15.  
    Abstract111)   HTML0)    PDF (748KB)(257)       Save
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    Electronic Journal of Liver Tumor    2023, 10 (1): 1-9.  
    Abstract297)      PDF (2166KB)(250)       Save
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    Electronic Journal of Liver Tumor    2019, 6 (4): 32-35.  
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    Electronic Journal of Liver Tumor    2021, 8 (3): 69-72.  
    Abstract110)      PDF (2782KB)(231)       Save
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